- Sánchez, Georgina - Voice Actress (Spanish)
- S.S. Hanami - Musical Performer
- S.S. Icarus - Steampunk Cosplay Group
- Sa, Kristine - Musician
- Sa'id, Amira - Bellydancer
- Sabat, Chris - Voice Actor
- Sackhoff, Katee - Actress
- Sadamoto, Yoshiyuki - Character Designer
- Sadie - Band
- Saeki, Shouji - Director
- Saga, Mighty Mike - Disc Jockey / Promoter / Graphic Designer
- Sager, Scott - ADR Engineer, FUNimation
- Sailor JAMboree - Cosplay Performers
- Saito, Chiho - Artist
- Saito, Chiwa - Voice Actress
- Saito, Kosuke - Disc Jockey
- Saito, Tomoko - Artist
- Saiyan, DJ - Disc Jockey
- Sakai, Stan - Artist / Creator
- Sakamoto, Chika - Voice Actress
- Sakamoto, Eizo - Singer
- Sakamoto, Kaeko - Producer, Bang Zoom! Entertainment
- Sakamoto, Maaya - Singer / Voice Actress
- Sakamoto, Ryosuke
- Saki - Singer
- Sakimoto, Hitoshi - Composer
- Sakuishi, Harold - Manga Creator
- Sakura Madams - Band
- Sakurabi, Chii - Singer
- Sakurabi, Katsushi - Animation Director
- Sakurai, Hiroaki
- Sakurai, Shushushu
- Sakurai, Susumu
- Sakurai, Takamasa - Writer / Producer
- Salad Time Soldiers - Cosplay Performers
- Saldana, Jason - Voice Actor, Roosterteeth Productions
- Sale, Tim - Comic Artist
- Sale Butler, Debra - Voice Actress
- Salia - Singer, Big Fighter Project
- Salo, David - Author / Linguist
- Salvaggio, Tony
- Salvatore, R.A. - Author
- Sambre, M.A - Artist
- Sampson, Tony - Voice Actor
- Samurai Delicatessen - Band
- Sanada, Asami - Voice Actress
- Sanazaki, Harumo - Manga Artist / Author
- Sander, Erik
- Sanford, Tim - Web Comic Artist, Nakama Comics
- Sanger, George 'Fat Man' - Composer / Author
- Sangster, Samantha R. - Cosplay and Lolita Fashion Designer, Blasphemina's Closet
- Sano, Soichiro - Producer
- Saolilith, DJ - Disc Jockey / Cosplayer
- Sarandon, Chris - Actor
- Sargent, Lia - Voice Actress
- Sarracini, Chris - Dreamwave Productions
- Sasaki, Akira
- Sasaki, Mikoi - Voice Actress
- Sasaki, Run - Voice Actress
- Sasaki, Wataru - Planner / Producer, Crypton Future Media
- Sasanuma, Akira - Voice Actor
- Satjawatcharaphong, Gritsada - Concept Artist
- Sato, Dai - Writer, Bandai Visual
- Sato, Junichi - Director
- Sato, Tatsuo - Screenwriter
- Sato, Yuzo - Animation Director
- Satoshi - Cosplayer
- Satsuki - Musician
- Saunders, Leo - Web Site Penciler, Chisuji
- Savage, Adam - TV Host, Mythbusters
- Savage, Carrie - Voice Actress
- Savage, Christian - Vice-President of Industry Affairs, Video Game Players Association
- Savage, Lorraine - Editor, Anime Hasshin
- Savage, Steven - Author
- Savage, Tom Danger - Photographer
- Savage Bandito, The - YouTube Personality
- savage genius - Band, Victor Entertainment, Inc.
- Savard-L'Herbier, Nicolas - Voice Actor
- Saviuk, Alex - Comic Book Artist
- Sawashiro, Miyuki - Voice Actress / Singer
- Saxton, Jad B. - Voice Actress
- Scandal - Band
- Schafer, RJ - Japanese Cultural Expert, Ana's Ikimaru
- Schemmel, Sean - Voice Actor
- Schilling, Curt - Pitcher / Video Game Developer, 38 Studios
- Schlanger, Stacey - Researcher, Ohio State University
- Schnuth, Aaron - Podcaster, Weekly Anime Review
- Schnuth, Diana - Podcaster, Weekly Anime Review
- Schodt, Fred - Author
- Schofield, Barb - Costumer
- Scholz, R. "Sketch" - Cosplayer / Illustrator / Flute Maker, Sketched Out Life
- Schons, Christopher - Artist
- Schrier, Paulie - Actor
- Schumie - Web Comic Creator, Autobrig
- Schwark, Mike - Web Comic Creator, Van Von Hunter
- Schwarze Sonne - Band
- Schwarzenegger, DJ - Disc Jockey
- Scootywok Sound And Light - Disc Jockeys
- Scott, Heather - Artist, Dragonmun Studios
- Scott, Kenn - Actor
- Scott-Frazier, Jan - Director / Translator / Jane-of-all-trades
- Scovil, Ron
- Sea of LCL - Band
- Searles, Lindsay - Cosplayer
- Sebastian, Trisha Lynn - Sequential Tart
- Sebree, William - Web Comic Artist, Is it Con Yet?
- Secret Secret - Band
- Seeberg, Xenia - Actress
- seek - Musician
- Seeley, Tim - Writer / Illustrator
- Segebarth, Alison - Creative Team, Hasbro
- Seidel, Lindsay - Actress
- Seitz, Patrick - Voice Actor
- Seki, Tomokazu - Voice Actor
- Seki, Toshihiko - Voice Actor
- Sekiguchi, Takafumi - CEO / Producer, CuriousFactory, Inc.
- Sekita, Mitsutoshi
- Select Start - Band
- Selia - Singer
- Senior, Geoff
- Senreich, Matt - Producer / Writer
- Sentar, Lianne - Writer
- Seobon - Musical Composer
- Sephiroth - Disc Jockey
- Serafilia - Band
- Serafini, Sebastiano - Model / Actor / Singer
- Seraphim - MegaTokyo
- Seraphim Guard
- Seraphina - Creator of Otaku Fusion Bellydance
- Seremedy - Band
- Serena, Ashley - Singer
- Serri, Daniela - Comic Artist, Dany&Dany
- Seth, Joshua - Voice Actor
- Seto, Andi
- Seto, Ben - Founder, Black Sheep Comics
- Sevakis, Justin - Director of New Media, Anime News Network
- Seven Story Coalition - Band
- Seward, Chris - Web Comic Creator, Brawl in the Family
- Shabet, Dave - Web Comic Creator, Dead Winter
- Shadix, Glenn - Actor
- Shadowfax - Disc Jockey
- Shall, Stefanie - Artist, Otakumals
- Shambaugh, Sue - Translator
- Shammers - DJ
- Shanks, Michael - Actor
- Sharp Three - Music Group
- Sharpnel, DJ - Disc Jockey
- Shatner, William - Actor
- Sheehan, Adam - Marketing Manager, FUNimation Entertainment
- Sheephead, DJ - Disc Jockey
- Sheh, Stephanie - Voice Actress
- Shen, Lien Fan - Manga Artist, Ohio State University
- Shepard, Blake - Voice Actor
- Shepard, Jewel - Actress / Writer
- Sheppard, Malcolm - Game Designer
- Sheppard, Mark - Actor
- Sheri, Mai - Cosplayer
- Sheridan, Kelly - Voice Actress
- Sherman, Delia - Author
- Sherman, Eric P. - President and CEO, Bang Zoom! Entertainment
- Shihori - Singer / Songwriter
- Shiki, Satoshi
- Shimabukuro, Hiroko "hiro" - Musician
- Shimamoto, Sumi - Voice Actress
- Shimamura, DJ - Disc Jockey, Dynasty Records
- Shimamura, Hidakazu - Character Designer
- Shimerman, Armin - Actor
- Shimizu, Aki - Mangaka
- Shimizu, Kenji - Producer
- Shimogama, Chiaki - Voice Actress
- Shimogasa, Miho - Character Designer / Animation Director
- Shin Ken Kai Nobara - Muso Jikiden Eishin Iaido Group
- Shing02 - Musician
- Shinick, Kevin - Writer / Actor / Creative Director
- Shinkai, Makoto - Director
- Shiokawa, Kanako - Japanese Folklorist
- Shioyama, Noiro - Animator / Creator
- Shiozaki, Yuji - Manga Artist
- Shiroboshi, Kaname - Cosplayer
- Shirohata, Bob - Director
- Shishido, Jun - Director
- Shizuno, Kobun - Director
- Shlasinger, Zev - Founder, Z-Man Games
- Shogunate, The - Band
- Shtibin, Elena - Artist
- Shuzilow.HA - Character Designer
- SID - Musicians
- Siddall, Brianne - Voice Actress
- Siembieda, Kevin - Founder, Palladium Books
- Silva, James - Game Developer
- Silvan, Rhea - Manga Artist
- Silver, Joe - Web Comic Inker, Chisuji
- Silverstein, Keith - Voice Actor
- Silvestri, Marc
- Simmons, Alissa - Cosplayer, Shoeless Cosplay
- Simmons, Mark - Gundam Fan
- Simmons, Vaughan
- Simon, Cliff - Actor
- Simons, Rosearik Rikki - Artist / Voice Actor, Studio Tavicat
- Simonson, Walter
- Simpson, Don
- Simpson, Lawrence - Amateur Voice Actor / Video Editor, Team Four Star
- Simpson, Matt - Web Comic Artist, Nuclear Powered Toaster
- Simpson, Scott
- Sin Comix
- Sinclair, Ian - Voice Actor / Director
- Singer, Amy - Musician / Singer, Pink Amys
- Sinterniklaas, Mike - Voice Actor / Director, NYAV Post
- Sirabella, John - President, Media Blasters
- Siravo, Christina - Illustrator
- Sirois, Myriam
- Sirois-Paradis, Elise - Author
- Sirtis, Marina - Actress
- SiSeN - Disc Jockey
- Situ, Dina - Web Comic Artist
- Siu-chong, Ken - Artist / Writer
- Sixh. - Fashion Designers
- Siya - Illustrator, Hyrogliphix, Inc.
- Sky Pirate - Cosplay Photographer
- SkyBlew - Musician
- Skye, Morgan - Costumer
- Slade, Heidi - Artist / Writer, Vampire Cow Productions
- Slants, The - Band
- Sleeping Samurai - Weapons Trainers
- Slightly Anime - Cosplay Performers
- Slott, Dan - Comic Writer
- SLY - Band
- Small, Jr., Louis - Comic Artist
- Smile, Apollo - Actress / Self-proclaimed Live Action Anime Girl
- Smile.dk - Band, Viverus Studios & Ninthwave Records
- Smiletron - Musician
- Smith, Adam - Costumer
- Smith, Andre "DJ Jinrei" - Disc Jockey
- Smith, Andy
- Smith, Anson - Web Comic Writer, Daze in a Haze
- Smith, Christopher - Voice Actor
- Smith, Chuck - Game Creator
- Smith, Doug - Artist / Voice Actor
- Smith, Felipe - Artist, MBQ
- Smith, JE - Writer / Artist, Better Comics
- Smith, Kevin - Actor / Writer / Producer
- Smith, Kirsty - Cosplayer, KhaosKostumes
- Smith, Michael - Web Comic Artist
- Smith, Natalie - Cosplayer
- Smith, Roger Craig - Voice Actor
- Smith, Scott - Web Comic Artist
- Smith, Toren - Translator, Studio Proteus
- Smithee, Adam - Web Comic Creator, The Apple of Discord
- Snackpants, Joey - Event Personality, Green Mustard Entertainment
- Snags, The - Band
- Snegoff, Greg - Writer / Voice Actor
- Sneko - Singer
- Snider, Hideko Tamura - Author
- Snow, Al - Actor
- Snyder, Dana - Voice Actor
- Snyder, Maria V. - Author
- So Be It - Band
- Sobolov, David - Voice Actor
- Society for Creative Anachronism - Historians
- Sock, Ed the - Sock Puppet, Ed & Red's Night Party
- Soejima, Yasufumi - Digital Director, Studio Gonzo
- SoftReset, The - Band
- Sohmer, Ryan - Web Comic Writer, Least I Could Do
- Solis Martial Arts Academy
- Solloway, Akemi - Lecturer
- Solusod, Micah - Voice Actor
- Sonoda, Kenichi - Character Designer
- Sophia - Band
- Sorbo, Kevin - Actor
- Sorensen, Jared A. - Game Publisher, Memento Mori Theatricks
- Sorich, Michael - Voice Actor
- Sorola, Gustavo - Co-Creator / Producer, Red vs Blue, Rooster Teeth Productions
- Sosa, Ryan
- Soskin, Marc - Amateur Voice Actor
- Sotira, Angelo - CEO / Founder, deviantART
- Soul Candy - Band
- Soulban, Lucien - Anime Game Creator
- Sound Bee HD, The - Band
- Southworth, Dan - Actor
- Soya, Manabu - Professional Wrestler, All Japan Pro Wrestling
- Space Invader - Cosplayer
- Spangler, Bill - Writer
- Spaulding, Ben
- Speed Demon, DJ - Disc Jockey
- Spellos, Peter
- Spencer, Spike - Voice Actor
- Spevack, Melodee M. - Voice Actress
- Spider's Kiss - Band
- Spiner, Brent - Actor
- Spiral Spiders - Band
- Spokane Kendo Club - Martial Arts Experts
- Spoony Bards, The - Musicians
- Sprague, Mark - Fandubber / Web Comic Artist, Dragon Mango
- Sprinkle, Diana X. - Artist, Radio Comix
- Spunk Da Bunny - Disc Jockey
- Spunks, The - Musicians
- St-Louis, Hervé - Founder, The Comic Book Bin
- St. Jean, Mandy - Voice Actress, Darkain Arts
- St. John, Jon - Voice Actor
- St. Louis Kimono-san - Geisha Themed Entertainers
- St. Louis Osuwa Taiko - Taiko Drummers
- Staite, Jewel - Actress
- Staley, Steve - Voice Actor
- Stan - Web Comic Creator, Parasomniac
- Stanworth, David - Web Comic Artist / Writer, Snafu-Comics
- Staples, Barbara - Cosplayer
- StarF - Musician
- Starlighthoney - Cosplayer, Cupcake Cosplay
- Starling, Jen - Web Comic Artist, 2wcOnline
- Starling, Renee - Webmaster / Writer, 2wcOnline
- StarSlay3r - Professional Gamer
- Staton, John - Artist
- Steacy, Ken - Artist
- Steam Century (HMA Badger) - Cosplay Group
- Steam Powered Giraffe - Band
- Steampunk Funk - Steampunk Costumers
- Steele, Allen - Author
- Steinberger, Aimee Major - Animator / Layout Artist
- Stelfreeze, Brian - Artist, Studio Gaijin
- Stephens, Danielle - Web Comic Creator, Goblins
- Stephens, Jerry - Web Comic Creator, Way of the Geek
- Stephenson, David - Physicist
- Stereopony - Band
- Stern, Ellyn - Voice Actress
- Sternbach, Rick - Sr. Illustrator / Tech. Consultant, Paramount Pictures
- Stevens, Eileen - Voice Actress
- Stevens, Richard - Web Comic Artist
- Stewart, Aaron - Web Comic Artist, Nakama Comics
- Stewart, April - Voice Actress
- Stewart, Patrick - Actor
- Stocker, John - Voice Actor / Director
- Stoklasa, Mike - Filmmaker, Red Letter Media
- Stone, J.D. - Voice Actor
- Stori, Moneca - Voice Actress
- Straczynski, J. Michael - Writer
- Strait, Sonny - Voice Actor
- Strang, Alex - Creator, Mr. Buckethead
- Strange, Patrick - Writer / Designer / Publisher / Producer, Temple Studios & Far East Productions
- Strangely, Dirk - Artist
- Straub, Kristofer - Web Comic Artist
- Straus, Jessica - Voice Actress
- Strauss, Katrina - Writer
- Strawberry Machine - Band
- Strom, Allison - Artist
- Strong, Tara - Voice Actress
- Strong Arm Productions
- Strong Machine 2 - Dancer
- Stroschein, Chuck - Cosplayer / Stunt & Dance Choreographer, Concept Galaxy
- Stuart, Eric - Voice Actor / Director / Musician
- Studio Happy Chicken
- Studio Udon - Artists
- Sturges, Donnie - Web Comic Writer, 2wcOnline
- Sturges, Jamie - Co-Founder, 2wcOnline
- ST~Prime - Band
- Suarez, Michael - Writer, Radio Comix
- Substantial - Musician
- Suburban Legends - Band
- Sudberg, Corinne - Amateur Voice Actor, Team Four Star
- Sugaya, Nobuyuki - President, AAC Production
- Sugimori, Miyuki - Candy Artist, Walt Disney World
- Sugiura, Koji
- Sugiyama, Noriaki - Voice Actor
- Sugizo - Musician
- Suicide Ali - Band
- Sukoshi Yoshi - Band
- Sullivan, Lee - Artist
- Sullivan, Timothy - Sake Enthusiast
- Sun Ergos - Theatre and Dance Troupe
- Sun String Quartet, The - Musicians
- SunaCosu - Cosplayers
- Sunga, Ramil
- Super 8-Bit Brothers - Band
- Surat, Daryl - Writer / Podcaster
- Sutherland, Catherine - Actress
- Suwa, Michihiko - Producer
- Suzaku Taiko - Taiko Drummers
- Suzan, The - Band
- Suzuki, Sally - Dancer, Japan Dance Association
- Suzuki, Takaaki - Writer
- Suzumi, Atsushi - Creator
- Suzumura, Nobuhiro - Director
- Swaile, Brad - Voice Actor, Ocean Studios
- Swann, Wendee - Voice Actress
- Swanson, Gerry - Game Designer
- Swasey, John - Voice Actor
- Sweetdiculous - Band
- SWEK - Musicians
- Swinging Popsicle - Band
- Symphonic Anime Orchestra - Musical Performers
- Synaptic Chaos Theatre - Improv Comedy Troupe
- Synergy - Dance Group
- Szawsum, DJ Andy - Disc Jockey
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